Dialysis is an easy and efficient technique to separate biomolecules according to their molecular weight and for the purification of proteins, dna, rna and oligonucleotids. Furthermore dialysis is also usefull for small bioactive compounds release or binding studies.
The MWCO (Molecular Weight Cut Off) is the cut frontier, which size of molecules can pass through
the membrane. The MWCO is always stated in Dalton (D or Da) and describes also the typical pore size of the membrane.
Important is that, these pores do not consist of „die-cut, regular holes‘‘. The pores are generated by the pressing of the thread-like cellulose material and consist of irregular cracks and openings. The passage of molecules through the membrane is influenced by the globular molecular conformation, the charge, the strength of the diffusion gradient and the hydration.
We are a specialist for laboratory dialysis and provide in our webshop dialysis solutions for most of the biomolecules, sample volumes and dialysis applications (dialysis, equilibrium dialysis). We provide ready-to-use and high-throughput systems like the Xpress Micro Dialyzer and the Gebaflex-tubes. We offer also dialysis tubings from CelluSpep and dialysis accessories.
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