Description
Precise Equilibrium Dialysis for Clinics and Research
The scienova ED300 provides a highly stable environment where diffusion can optimally reach equilibrium. This makes the Equilibrium Dialyzer an indispensable tool for laboratory dialysis, buffer exchange, desalination, and protein synthesis.
Key Features & Benefits
- Dual-Access Design (Simplified Access): Allows both the sample and the dialysate to be loaded and recovered directly from the top, without having to use the chambers. This is essential for assays where the target molecule (e.g., a free hormone) is measured directly within the dialysate.
- Minimized Sample Loss: The regenerated cellulose membrane reduces non-specific adsorption of proteins, hormones, and small molecules, ensuring precise and reproducible measurement results.
- Scalable Throughput: The ED300 is supplied in a ready-to-use 96-deep-well plate format. The flexible system can process from a single sample up to 96 samples simultaneously, significantly reducing costs per test.
- Automation-Compatible: Fully compliant with the SBS microplate standard, the ED300 integrates seamlessly into automated liquid handling workflows (such as CyBio® FeliX), maximizing laboratory efficiency and reducing manual handling errors.
Specialized Application Areas
- Clinical Diagnostics: Determination of free hormones (including free testosterone, free cortisol, FT3, and FT4).
- Pharmacokinetics: Comprehensive protein-drug binding studies and ligand binding assays.
- Environmental Analysis: Investigation and monitoring of pollutant binding to humic acids or other environmental carriers.
- Biotechnology: High-precision protein-protein and protein-DNA interaction studies.
Technical Specifications
| Sample Volume | 50 µl – 300 µl |
|---|---|
| Buffer Volume | Up to 1,400 µl (in deep-well plates) or 3,600 µl (in microcentrifuge tubes) |
| MWCO Options (Cut-offs) | Available in various molecular weight cut-offs (e.g., 3.5 kDa, 6–8 kDa, 12–14 kDa) to match specific target molecules |
| Material | Medical grade polypropylene plastic |
| Format Standard | Compatible with SBS microplates / 96-deep-well plates |

